Overview of Selected Chemical Compounds and Intermediates

Overview of Selected Chemical Compounds and Intermediates

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one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is often an impurity linked to bortezomib, a proteasome inhibitor used in the remedy of several myeloma. Its synthesis or examine is crucial for guaranteeing the purity and security from the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor while in the synthesis of abiraterone acetate, a drug Utilized in the therapy of prostate cancer by inhibiting androgen production.
Imatinib Intermediate (CAS NO. 152460-ten-one): A crucial compound inside the synthesis of imatinib, a drug that targets unique sorts of cancer, which include Continual myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Employed in the synthesis of docetaxel, a chemotherapy medication that treats several cancers like breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are typically intermediates within the synthesis of gemcitabine, an anti-cancer drug. Their research is very important for optimizing the production course of action and ensuring large purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-five): Lapatinib is employed to deal with breast most cancers, and these intermediates are involved in its creation.
Fulvestrant Intermediates: Fulvestrant can be an estrogen receptor antagonist used in the treatment method of breast most cancers. Numerous intermediates help in the synthesis of this drug.
Paclitaxel Aspect Chain Acid (CAS NO. 949023-sixteen-nine): This intermediate is used in the synthesis of paclitaxel, a chemotherapy drug powerful in managing cancers such as ovarian, breast, and lung cancer.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug Utilized in the cure of colorectal most cancers and small cell lung 7-dihydro-4-oxo-1H-pyrrolo[2 cancer.
3-Amino-1-hydroxyadamantane (CAS 702-82-9): This compound is linked to the synthesis of adamantane derivatives, which have numerous programs, such as antiviral Homes.
Vildagliptin Intermediates: Utilized in the manufacture of vildagliptin, an oral drug for δ-lactone variety 2 diabetes that inhibits the enzyme DPP-4 to regulate blood sugar ranges.
4. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-one): This compound is linked to the synthesis of varied gluconic acid derivatives, which happen to be Employed in food stuff, pharmaceutical, and industrial purposes.
Canagliflozin Intermediate 2: A precursor inside the synthesis of canagliflozin, a medication employed to handle kind 2 diabetes by inhibiting sodium-glucose co-transporter 2 (SGLT2).